
                  ---------------------------------------------
                  TINKER -- Software Tools for Molecular Design
                  ---------------------------------------------

                             Version 4.2   June 2004
                   Copyright © 1990-2004   Jay William Ponder

TINKER is a modular program package for molecular mechanics-based potential
energy calculations, geometry optimization, molecular dynamics simulation,
distance geometry and structural analysis.

------------------------------------------
Selected References for the TINKER Package
------------------------------------------

P. Ren and J. W. Ponder, J. Phys. Chem. B, 107, 5933-5947 (2003)

P. Ren and J. W. Ponder, J. Comput. Chem., 23, 1497-1506 (2002)

R. V. Pappu, R. K. Hart and J. W. Ponder, J. Phys. Chem. B, 102, 9725-9742
(1998)

M. E. Hodsdon, J. W. Ponder and D. P. Cistola, J. Mol. Biol., 264, 585-602
(1996)

C. E. Kundrot, J. W. Ponder and F. M. Richards, J. Comput. Chem., 12, 402-409
(1991)

J. W. Ponder and F. M. Richards, J. Comput. Chem., 8, 1016-1024 (1987)

----------------------------------------
Conditions for Use of the TINKER Package
----------------------------------------

The TINKER software is registered under U.S. Copyright Law. The source code
was developed by the author and is distributed solely through the Department
of Biochemistry and Molecular Biophysics at Washington University. Its use is
subject to the following conditions:

(1)  Use of this software is restricted to the individual, laboratory or
organization to which it is supplied. The package and portions thereof may
not be sold nor may copies be distributed to third parties without the
express permission of the author and Washington University.

(2)  This software package is provided on an "as is" basis. The author in no
way warrants either this software or results it may produce.

(3)  The author is under no obligation to provide any services by way of
maintenance, updates or corrections for this software.

(4)  Reports or publications resulting from use of this software package must
contain an acknowledgment in the form commonly used in academic research.


                _____________________________________  Signature

                _____________________________________  Name

                _____________________________________  Date

                _____________________________________  Organization

                _____________________________________  Address

                _____________________________________

                _____________________________________  E-mail


If the above conditions are accepted, please sign this form and return a copy
by mail to the following address:

                Dr. Jay W. Ponder
                Biochemistry & Molecular Biophysics, Box 8231
                Washington University School of Medicine
                660 South Euclid Avenue
                St. Louis, MO  63110   U.S.A.
